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Rather, sleep apnea patients exhibited increased TNF concentrations in the afternoon, the time period during which concentrations in normal control subjects are at a minimum

Physicians may opt to treat these patients and monitor for improvement of metabolic markers, particularly in populations at high risk of clinical vitamin B 12 deficiency, or observe these patients and periodically reassess their levels of vitamin B 12 , homocysteine, and/or methylmalonic acid

PLoS ONE 5:e12238

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