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3.6 Traumatic brain injury Traumatic Brain Injury (TBI) is followed by a cascade of secondary injuries, including the release of excitatory neurotransmitters and Fe 2+ , OS, LP, and the accumulation of ROS, all of which induce ferroptosis (Anthonymuthu et al., 2018)

National Institute of Mental Health: Anxiety Disorders

Anaesthetic drugs protect against ferroptosis or promote tumour cell ferroptosis through the System xc-/GPX4 pathways, iron metabolism, lipid metabolism and other pathways

Dringen R, Gutterer JM, Gros C, Hirrlinger J

In addition, complete FXN-knockout mice are embryonic lethal, and thus our best mouse models are those which are temporally conditional FXN deficient or those which exhibit tissue-specific FXN loss (Cosse et al., 2000)

[DOI] [PMC free article] [PubMed] [Google Scholar] 55.Murillo A.G., Fernandez M.L