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Yamamoto et al., 2015
10.1021/ar200193f 9 BowmanA
Frataxin silencing promotes longevity through multiple mechanisms, including mitophagy activation, HIF-1 signaling, and ferroptosis inhibition (Schiavi et al, 2023, 2015, 2013)
However, given that ANGPTL3 activity is positively correlated to increased levels of phospholipid-rich HDL, which is highly active at cholesterol transport, there may be risks to blocking ANGPTL3 activity entirely

"Electronic Nose Created To Detect Skin Vapors"
Genetic and structural insights into broad neutralization of hepatitis C virus by human V H 1-69 antibodies