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Response timelines vary

While the magnitude of this effect varies among individuals, even modest increases in metabolic rate can support sustained fat loss over time

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in 2017, it has been the subject of approximately 15-20 peer-reviewed publications spanning metabolic disease, muscle biology, cardiovascular research, neurodegenerative disease, and cancer metabolism

Use in the evening - this allows overnight contact time and avoids UV exposure while the product is on the scalp