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Scheller U., Lee C., Seibler P., et al., Impaired Neurogenesis and Synaptogenesis in iPSCderived Parkinson's Patient Cortical Neurons With D620N VPS35 Mutation, BioRxiv (2024), 10.1101/2024.08.07.606995

Distinct mesenchymal cell populations generate the essential intestinal BMP signaling gradient

Supplementing and maintaining Glutathione levels can slow the ageing process down

Ninety-five percent of the dietary glutamate is metabolized by intestinal cells in a first pass

From adjusting lipid composition, vesicle size, and surface properties to developing specialized systems such as liposome-exosome hybrids or targeted brain delivery, we provide formulations that meet precise preclinical research objectives

The anti-apoptotic effects of luteolin can be mediated via several mechanisms such as reducing the levels of caspase-3 and 9 and improving the B-cell lymphoma protein 2/Bcl-2-associated X protein (Bcl-2/Bax) ratio, as it was reported in in vitro models of AD [61] and PD [62], as well as in vivo models of AD [63, 64] and PD [65, 66]
