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However, this is very important: enthusiastic anecdotal reports are not a substitute for controlled clinical trials

It remains to be established whether this subset of patients differs from antibody-negative patients in terms of underlying patho-physiology and response to standard or immunomodulatory treatments
Week 3-4: Dark spots start to appear lighter

RORt protein modifications and IL-17-mediated inflammation

Available online: 97.WHO www.who.int

An overview of the mechanisms of ERS is given in ( Figure 2 )
