bpc-157 clinical evidence randomized trial humans as an Investigational Peptide Therapeutic: Biopharmaceutical Challenges, Formulation Strategies, and Translational Development Barriers How does the peptide BPC-157

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doi: 10.1001/jamanetworkopen.2023.4714 93

Shifts in GABAergic tone in particular can suppress the firing of dopamine neurons in the ventral tegmental area (VTA), which is the origin point of the mesolimbic dopamine pathway that drives reward

Timing considerations Morning and evening dosing spreads peptide exposure throughout the day

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