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The identification of CD38 as a key modulator of NAD + metabolism in the context of cell signaling, aging, and tumor biology suggests that the enzyme is a target of promising therapeutic potential

Remarkably, the susceptibility to cuprizone, extent of hydrocephalus, spatiotemporal pattern of de- and remyelination or the glial reaction are varying between species, mice strains or simply between different brain regions (Carlton, 1976

Within a research context, this compound is studied for its interactions with tissue repair mechanisms , angiogenesis-related pathways , and cellular signaling processes

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10.1016/j.annonc.2020.08.209 239

10.1523/JNEUROSCI.5002-13.2014 [DOI] [PMC free article] [PubMed] [Google Scholar] 341.Tenner AJ, Stevens B, Woodruff TM