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Description
Vitamin B12 can cause dermatitis, acne, and other skin-related conditions when taken in excess, according to a review in the American Journal of Clinical Dermatology

This combination of gene regulation, ECM modulation, and anti-inflammatory signaling underscores the peptide's pleiotropic nature in laboratory investigations

Teichman SL, Neale A, Lawrence B, Gagnon C, Castaigne JP, Frohman LA

Mecobalamin - NCI Drug Dictionary [Internet]
The vitamin/mineral supplement in this study contained molybdenum (150 mcg for a 30 kg child), so this may also have contributed to increases in sulfate levels
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