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Identification of Ferroptosis as a Novel Mechanism for Antitumor Activity of Natural Product Derivative A2 in Gastric Cancer

Galletti, G

Excess ROS acts as a second messenger and regulates the function of important proteins, including Kelch-like ECH-associated protein 1 (Keap1), protein kinase C (PKC), and IB kinase by interacting with the cysteine residues (known as redox sensors) and causes their oxidation [10,25]

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Adipose-MSC exosomes accelerate skin regeneration via hyaluronan synthase-1, while MSC-exosomes in the lung suppress inflammation and EMT, limiting fibrosis