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Warfarin has been recognized to promote acute kidney injury in case of excessive anticoagulation levels

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A decrease in the expression of the pro-ferroptotic proteins ACSL4, TFR1, and VDAC2/3 and a decrease in dihydroethidium (DHE) fluorescence, iron, malondialdehyde (MDA), and myeloperoxidase (MPO) were further observed in metformin-treated mice

Ses bienfaits documents couvrent quatre domaines majeurs : la neutralisation des espces ractives de l'oxygne, la dtoxification hpatique de phase II, le soutien de la fonction immunitaire et la protection contre le vieillissement cellulaire