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163 At the lesion core therefore, all neural cells die by necrosis, which leads to a massive release of damage-associated molecular patterns (DAMPs), including release of glutamate and ATP, which propagate excitotoxicity

(PDF 1383 kb) Additional file 9: (download XLSX Tables S2 to S7

Reduced and oxidized glutathione in the substantia nigra of patients with Parkinsons disease

An overabundance of ROS disrupts intracellular redox balance, triggering oxidative stress and elevating susceptibility to ferroptosis

Moreover, although we enrolled only depressed bipolar patients, Berk et al examined NAC as a maintenance treatment, enrolling bipolar patients irrespective of current mood state

CBG and Glutathione: The Dynamic Duo CBG elevates the efficiency of glutathione , making it more impactful in neutralizing oxidative stress and inflammation