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At the same time, there is a growing need to identify substances with protective effects, known as cytoprotectors, which are non-toxic to healthy cells and do not diminish the therapeutic efficacy of chemotherapy

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also showed significant increases in serum concentrations of asymmetric dimethylarginine (ADMA), enhanced inhibition of NOS, enhanced catabolism of Arg, increased levels of ornithine (Orn) and proline (Pro), and decreased Arg/Orn ratio in patients with asthma and obstructive sleep apnea (OSA)