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doi: 10.1016/j.jhep.2020.07.034

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We provide evidence that late-life (23.5 mo.) initiated intermittent MOTS-c treatment (3x/week) can increase physical capacity and healthspan in mice

These results support critical roles for coregulators, and their interactions with other AR-recruited proteins in shaping the AR cistrome and mediating its transcriptional output (Fig

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