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Glutathione plays an important role in the detoxification of ethanol (alcohol) and acute alcohol consumption leads to Glutathione depletion in the liver and other tissues (PMID 1930162)

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This review comprehensively elucidates the regulatory networks of ferroptosis in OS, with a specific focus on the System Xc/Glutathione Peroxidase 4 (GPX4) antioxidant axis and lipid metabolism