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utilized shRNA silencing of the microglial GPX4 gene to assess the anti-inflammatory effects of saikosaponin B2 (SSB2) in LPS-induced primary microglia and CUMS-induced mouse models of depression

BhatiaDChungKNakahiraKPatinoERiceMTorresLet alMitophagy-dependent macrophage reprogramming protects against kidney fibrosis

Vitamin B12 DesensitizationMechanism and Effectiveness Drug desensitization is mainly used in patients who have experienced hypersensitivity reactions to a specific drug in the absence of alternative treatment options [109,110]

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These effects of E2 are mediated via MC4 receptor because E2 is unable to induce anorexia when the MC4 receptor antagonists Shu 9119 or agouti-related peptide (AgRP) are applied concomitantly with E2 administration in rats (70)