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[DOI] [PMC free article] [PubMed] [Google Scholar] Vazquez F, Lim J-H, Chim H, Bhalla K, Girnun G, Pierce K, Clish CB, Granter SR, Widlund HR, Spiegelman BM, et al

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The concentration was far below standard GHK-Cu serums (0.02% vs 1 to 2%)

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Several in vitro and in vivo therapeutic studies have shown that SOD2 lipophilic mimic, Mn (III) meso-tetrakis (N-n-hexylpyridinium-2-yl) porphyrin, (H2O) MnTnHex-2-PyP5 + (MnHex) can cross the BBB and accumulate in mitochondria than cytosol (Leu D et al., 2017