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Researchers are exploring its impact on gut-brain signaling, tight junction protein expression, and cytokine modulation, though these mechanisms remain under active investigation

These include the antimitotic microtubule inhibitors (e.g

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The specific amount of weight you might lose from Zepbound is uncertain, but significant weight loss ranging from 35.5 lb (16.1 kg) to 52.0 lb (23.6 kg) was observed in the 72-week SURMOUNT-1 clinical trial, which compared different Zepbound (tirzepatide) doses to a placebo (inactive treatment)