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It affects the canonical splice acceptor site of exon 3 resulting in either a frameshift with premature translational arrest, or exon skipping

This includes people with kidney and liver disease, those with diseases related to the blood, and women who are pregnant

Some people absorb and store vitamins more efficiently than others, which means they might need injections less frequently

There are also cases where patients with low B12 levels have problems with fertility or are more likely to develop dementia

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Occasional Injections : Annual vaccinations or monthly long-acting formulations balance efficiency and comfortstandard recommended needle sizes from reliable needle factory sources suffice