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Mohan Y, Jesuthankaraj GN, Ramasamy Thangavelu N
Nature (2021) 593:4359
Curr Treat Options Neurol 21:4
Despite these promising early findings, there is insufficient evidence to support the inclusion of FMT in standard ALS treatment
There are also pleiotropic effects of some compounds which indirectly re-activate survival pathways (e.g., compensatory activation of other RTKs or augmented antioxidant defenses) which can suppress the net anticancer effect, and in extreme circumstances can temporarily maintain the survival of stressed malignant cells
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