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Statins, along with inhibiting the activity of HMG-CoA reductase enzyme, also block the pathway leading to the production of CoQ10 [12, 13]

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PMID: 27517151 Citations are provided for research reference

Given that aging is associated with a decline of mitochondrial functions along with the development of aging-related diseases, and given that the tissue and circulating levels of MOTS-c fall with age, it is compelling to hypothesize that declining MDP levels are also related to age-related metabolic deterioration

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