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FerroLOXIN-1 and -2 also protect against IR-induced ferroptosis by inhibiting 15-LOX, though the drug exclusively interacts with the 15-LOX/PEBP1 complex, similar to Fer-1

[DOI] [PMC free article] [PubMed] [Google Scholar] Li Q, Han X, Lan X, Gao Y, Wan J, Durham F, Cheng T, Yang J, Wang Z, Jiang C, et al

Lee MS, Advani SM, Morris J, Jiang ZQ, Manyam GC, Menter D, McIntosh Broom B, Eng C, Overman MJ, Maru DM, Hamilton SR, Kopetz S

doi: 10.1016/j.cub.2021.02.049 78 MaranoMAnziniGSaltarocchiLRicciutiRCaponeFTanHet al
