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HPA axis, hypothalamic-pituitary-adrenal axis

Thus, the optimal dosing and therapeutic window for NAC in EDC warrants further investigation

The woman presented with a florid, red, spotty and pustular rash over her face, neck and shoulders

GSH is found predominantly in its reduced form, except in the ER, where it exits mainly as oxidized glutathione (GSSG), GSSG being the main source of oxidizing equivalents to provide the adequate environment necessary for favoring disulfide bond formation and the proper folding of nascent proteins (61)

P = 0.016)

Concomitant identification of biomarkers for ferroptosis is also required for more rigorous inclusion/exclusion into clinical trials and robust evaluation/formal testing of novel therapies targeting the ferroptotic cascade