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In organisms, including humans, ROS and free radicals are produced during metabolic and immune system function

doi: 10.3109/00498258609038976

Acknowledging and accounting for these determinants is the cornerstone of translating SFNs promise into predictable and potent clinical outcomes

Conclusion Although more specific mechanisms need to be investigated, it is well accepted that epigenetic events are important in normal biological processes as well as in tumorigenesis and that the epigenetic status is usually widely altered during cancer initiation

Yuan, A., Kumar, A., Peterhoff, C., Duff, K

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