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Drug therapies are commonly used to bring clinical symptoms and biochemical abnormalities under control, either while the patient attempts diet and lifestyle changes or in the event a patient does not improve sufficiently with nutrition and lifestyle strategies

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Wu Y, Wang J, Zhao T, Chen J, Kang L, Wei Y, et al

Apart from fructose-6-phosphate engaging in bidirectional metabolism with the non-oxidative phase of the pentose phosphate pathway or proceeding toward glycolysis or hexosamines, it also serves by forming a regulatory molecule

Acknowledgements This work was supported by the National Key R&D Program of China (2020YFA0710700, X.L.Y.), the National Science and Technology Major Projects of New Drugs (2018ZX09201018-013, P.C.), the National Key Research and Development Program of China (No

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