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doi: 10.1158/2326-6066.Cir-20-0384

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To this end, we first optimized the peptide-to-bead ratio and split the beads contained in one spin column from the kit into five aliquots, each one of them used to enrich ~250 g of starting tryptic peptide material

The enzyme NNMT normally changes nicotinamide, a form of vitamin B3, by using methyl groups, which lowers nicotinamide adenine dinucleotide (NAD+) levels