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Thats true for clozapine, which is predominantly metabolized at CYP1A2, though it has several auxiliary pathways

Actin depolymerization disrupts tight junctions via caveolae-mediated endocytosis

G., Gaetz, W., Bloy, L., Wang, D.-J., Blaskey, L., Kuschner, E

[PubMed: 24515955] 501

To evaluate cancer cell lines exhibiting chronic NRF2 activation, we evaluated 913 candidates from the Cancer Dependency Map ( 16,17 for cell lines with evidence of both increased NRF2 target gene expression and NFE2L2 genetic dependency, termed NRF2 on cells (Extended Data Fig
