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GSH depletion cause indirectly formation of endotoxins in the cytoplasm of pigmented SN cells that contribute to the degeneration of these neurons in PD Figure 2. As previously mentioned the activity of -GT is up-regulated significantly in the parkinsonian SN [61]

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The fight or flight process (sympathetic stimulation) reduces blood supply to the gut

10.1262/jrd.2022-103 87 TripathiS

& Aharonowitz, Y

Due to its structural properties and biological interactions, BPC-157 is widely studied for its potential role in cellular adaptation, healing and repair mechanisms, and growth factor modulation