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The flow cytometry results demonstrated that the RGSH intervention could markedly reduce cell death caused by ferroptosis (Fig

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Experimental studies indicate that supraphysiological testosterone exposure increases reactive oxygen species generation within cardiomyocytes while reducing the activity of endogenous antioxidant enzymes, including superoxide dismutase and glutathione peroxidase (72)

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10 mM by day 28

This highlights the potential of these agents as a viable therapeutic option for melasma management, addressing both aesthetic concerns and underlying hormonal factors