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Some authors recommend anatomopathological examination for diagnostic confirmation, although others sustain that the diagnosis is only clinical and follow-up is necessary to investigate changes in size, shape, and color of the lesion

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Reloading of intracellular stores with Ca 2+ , after cessation of the phospholipase C-linked stimulus, occurred just as rapidly as when the stimulus was present (Parod & Putney, 1978;Casteels & Droogmans, 1981)

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