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While ideally, consuming fewer calories than you burn leads to fat breakdown for energy, this isnt always the case

10.1186/s12951-021-00916-2 59 DickinsonA

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Furthermore, they exhibited degeneration of retinal ganglion cells, optic nerve head excavation and reduction in optic nerve thickness, generalized severe irregularity of retinal vessels, faint presentation of choroidal vessels, and severe optic nerve disc atrophy
