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Additionally, immune checkpoints modulate ferroptosis in a cell-specific manner

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Under stressful conditions, spermatozoa undergo an intrinsic apoptotic pathway characterized by the generation of mitochondrial ROS, the loss of mitochondrial membrane potential, caspase activation, phosphatidylserine exposure, and oxidative DNA damage [15]

Jiang Z-B, Wang W-J, Xu C, et al

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