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macranthoides has been grouped into the Flos Lonicerae ( Shan Yin Hua ) instead of the Flos Lonicerae japonica ( Jin Yin Hua ) by the China Pharmacopoeia since 2005

This is at least partly due to suppressed oxidative stress as a result of decreased NOX expression and improved eNOS and SOD expression (Finch et al
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While there is no officially established "upper limit" by the FDA, most clinical research suggests that up to 2,000 mg per day is well-tolerated by most adults for short periods

10.1016/j.bcp.2017.12.015PubMed Abstract | CrossRef Full Text | Google Scholar 149 van de KerkhofE

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