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And the maximum tolerable dose was 45 mg/kg/day, IP, for 7 days [29]

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Further, brain MRI detected significant microstructural changes in areas such as the insula, supramarginal, and inferior frontal gyri, reflecting neuroplastic changes induced by HBOT

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A useful way to think about bakuchiol is this: it gives the person who wants retinol-adjacent results another route, especially if they care about sensitivity, redness-prone skin, or daytime compatibility

Nature 225 , 12071209 (1970)