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Description
El cobre en s es un cofactor esencial de numerosas enzimas implicadas en la sntesis de colgeno (lisil oxidasa), la defensa antioxidante (superxido dismutasa) y la produccin de melanina (tirosinasa)

This occurred in the absence of detectable changes in their total protein levels (Fig
Silencing ACSL4 in the substantia nigra can prevent dopaminergic neuron death and motor defects in PD mice, and inhibition of ACSL4 activity with triacsin C can improve the PD phenotype
PMID: 13 AbdulaiPMOssaiCEzejioforANFrazzoliCRoviraJEkhatorOCet al

It was located in association with the inner membrane toward the cytoplasmic side, suggesting easy accessibility to extracellular peptides (Takahashi and Watanabe, 2004)

[Abstract]2026 Mar 12:804:153353
