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In contrast to a single biomarker-based signature, a multigene signature model is more accurate for predicting the prognosis of patients with breast cancer

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doi: 10.1210/endo12452509 230 ChenDYangWHanSYangHCenXLiuJet al

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Therefore, in line with 3 R animal experimental principles, we chose to conduct our proof-of-concept study directly in elephants since an in-target-species trial in a real-world setting provides an accurate reflection of the vaccines safety and immunogenicity, avoiding reliance on models that poorly recapitulate elephant immunology