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Representative western blot images and quantification of s , liver, t , gastrocnemius, u , BAT and, v , iWAT of DIO mice treated with vehicle or 325 nmol/kg EB1002 18 h prior to injections with a mock solution or insulin (n = 5 (vehicle/mock), n = 6 (EB1002/mock, vehicle/insulin) n = 7 mice (EB1002/insulin))

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Zeng et al., 2015

On the other hand, maintaining the pH of the formulations (especially liquid formulations) within the range of 4.5 to 6.5 ensures optimal drug permeation, minimises nasal irritation, and inhibits bacterial growth

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(2001) Effect of synthetic pineal tetrapeptide (Ala-Glu-Asp-Gly) on melatonin secretion by the pineal gland of young and old rats [PMID: 11335898, Anisimov VN et al