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Melatonin has two important functional groups that determine its specificity and amphiphilicity: the 5-methoxy group and the N-acetyl side chain

Although the inflammatory response in the GI tract of a patient with IBS might not be as out of balance as it is in IBD patients, even low-grade imbalance can contribute to intestinal damage in the GI tract that leads to gastrointestinal motor dysfunction

They also cross the blood-brain barrier, which is why mental clarity and focus are commonly reported alongside the physical benefits

Blocks the enzyme responsible for triggering melanogenesis in the skin

Gao P, Shi Y

And if so, whats the science behind it