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The secondary mechanism is passive diffusion: approximately 1% of any oral B12 dose is absorbed by passive diffusion across the intestinal lining, independent of intrinsic factor and without saturation

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For acute injuries, split dosing (half the daily amount every 12 hours) maintains more consistent tissue levels

[65] [2] [80] For humans, the bioavailability from eggs is less than 9%, compared to 40% to 60% from fish, fowl, and meat