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Sustained hedgehog signaling in medulloblastoma tumoroids is attributed to stromal astrocytes and astrocyte-derived extracellular matrix
Interestingly, in contrast to the HO-1 antiatherogenic actions, the expression of its transcriptional regulator Nrf2 leads to proatherogenic effects instead

Then the activation of TNF could improve the synaptic signalling

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CY: Writing review & editing, Visualization, Data curation, Conceptualization