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Additionally, photosynthetic eukaryotes generate oxygen as a byproduct of photo-synthesis that is converted to toxic metabolites under abiotic stress conditions which could damage biomolecules of the photosynthetic apparatus

Biochemistry 40 : 1413414142 Klatt P, Molina EP, De Lacoba MG, Padilla CA, Martinez-Galesteo E, Barcena JA and Lamas S (1999) Redox regulation of c-Jun DNA binding by reversible S -glutathiolation

The GCLM gene is located on chromosome 1p22.1 and is composed of 9 exons that generate two alternatively spliced mRNAs that encode proteins of 274 amino acids (isoform 1) and 252 amino acids (isoform 2)
Nanoparticles ruptured and then Mn 3+ reduced to Mn 2+ for PDT and MRI in a high level GSH environment, while DOX was applied for CT

& Collins, J

Future therapies might target specific ROS sources, like NOX inhibitors for inflammation
