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The demethylation of PP2A is facilitated by the action of protein phosphatase methylesterase-1 (PME-1)

Transient receptor potential A1 receptor-mediated neural cross-talk and afferent sensitization induced by oxidative stress: implication for the pathogenesis of interstitial cystitis/bladder pain syndrome

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In China, combination therapies involving icaritin are the subject of numerous ongoing clinical trials for the treatment of hepatocellular cancer (NCT03236636, NCT03236649, ChiCTR2300077991, and ChiCTR2300077987) and pancreatic ductal adenocarcinoma (ChiCTR2300077907)

Depending on the specific disease context, the occurrence of ferroptosis can be either pathogenic or therapeutic
25 The dosing schedule was 1000 g daily for 7 days, then 1000 g once per week for 1 month, then 1 1000 g injection monthly for 6 months