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1 Introduction An unprecedented worldwide spread of coronavirus-2 of the severe acute respiratory syndrome (SARS-CoV-2), the cause of coronavirus disease 2019 (COVID-19), has imposed tough challenges on the health and medical infrastructure around the world (1)

the FDA has stated it lacks sufficient information to know whether the substance would cause harm when administered to humans Evidence snapshot: The evidence base is almost entirely preclinical, decades of animal (largely rat) studies, mostly from one Croatian research group (Sikiric et al., University of Zagreb), with a single small human trial under the brand name "Bepecin" (around 2015) that did not lead to any FDA-approved use

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