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Second, C/EBP- LIP down-regulated Pgp and up-regulated calreticulin that triggered the dendritic cell (DC)-mediated phagocytosis of tumor cell, followed by the activation of anti-tumor CD8 + T-lymphocytes upon doxorubicin treatment

To overcome this, Spinetti et al

However, we demonstrated that C/EBP phosphorylation at Thr 235 is ERK1/2-dependent and unaffected by AKT or mTOR down-regulation

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