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The label expansion was supported by two Phase III trialsa 12-week induction study and a 52-week maintenance studyboth of which met the primary endpoint of clinical remission

5 Mechanism of induction of cancer cells death by essential oils
Discovery of Novel Sulfonylurea NLRP3 Inflammasome Inhibitor for the Treatment of Multiple Inflammatory Diseases
GSS facilitates the reaction between -glutamyl cysteine and glycine, which ultimately results in the formation of GSH
10.1038/s41387-018-0017-1 19

Steinherz PG, Redner A, Haimi J, Meyers P, Andreeff M