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A 24-week study involving 485 participants with peripheral arterial disease showed that propionyl-L-carnitine increased maximum walking distance by 73% and improved pain-free walking distance compared to the placebo groups

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The results ranked their contributions in descending order as follows: Moheibacter , L-carnitine, Gaetbulibacter , N,N,N-trimethyllysine, alpha-linolenic acid, betaine, Cnuella , Lacibacter , and MPO