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To date, effect of oral vitamin B12 treatment has not yet been adequately documented in patients presenting with severe neurological manifestations

Vitamin B12 (Methylcobalamin) & Biotin- contribute to normal psychological function and support energy-yielding metabolism, playing a key role in brain health and nervous system function

Silybin is a strong free-radical scavenger as well as an anti-inflammatory

Rankl, receptor activator of nuclear factor B ligand

With the help of the remedy WJ-A, it minimized TNF-alpha and nitric oxide, increased ATP and antioxidant levels in the bladder and normalized the ion disorders

Studies using cells further confirm the antioxidant effect of esculetin, which regulates the expression of various antioxidant proteins (26-28)