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If you are struggling with alcohol misuse or AUD, you are not alone

The joints of people who do not move enough or those who are bed ridden for long also suffer as the cartilage tissue does not feed and is thus damaged

Chronic inflammation from misuse can trigger post-inflammatory hyperpigmentation on darker skin tones

Classically activated (M1) macrophages arise following exposure to interferon- (IFN) and/or tumor necrosis factor (TNF), express high levels of cytokines IL-1, IL-6, and IL-23, and are adept at producing ROS, all traits as possible which make them highly effective killers during infection or in response to cancer

doi: 10.3389/fphar.2018.00911 94 RugemaliraERoineIKuligowskiJSnchez-IllanaPieiro-RamosJDAnderssonSet al

Leukotriene B4 is an arachidonic acid metabolite produced via the lipoxygenase pathway that strongly attracts neutrophils to sites of tissue injury