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Description
Acta (BBA)-Molecular Cell Res
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By addressing both the molecular and the cellular aspects of proteostasis, these strategies offer promising avenues for the treatment of disorders associated with protein folding and dysproteostasis
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SLC7A11 was identified as a druggable target downstream of the MCU-Nrf2 axis (Wang et al., 2022)
Elevated levels of HNE-protein adducts have been observed both in Lewy bodies within the SN and in the CSF of PD patients (82, 86)
