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Drug-induced liver injury: Cascade of events leading to cell death, apoptosis or necrosis

Katzenschlager R, Sampaio C, Costa J, Lees A

This reduced systemic utilization indicates the overall effect of intestinal breakdown, deficient absorption, and rapid metabolic transformation

Host carbon sources modulate cell wall architecture, drug resistance and virulence in a fungal pathogen

doi: 10.1038/ajg.2012.126

Through precision targeting of TAMs, it may be possible to optimize therapeutic approaches against immunosuppressive and tumor-promoting macrophage subpopulations, thereby improving clinical outcomes for patients with ovarian cancer